Out of Patients with Matthew Zachary
Out of Patients with Matthew Zachary
The longest-running independent healthcare podcast, Out of Patients with Matthew Zachary has supplied 17 years of unfiltered truth about American healthcare. A 30-year brain cancer survivor, Matthew built the young adult cancer movement from scratch. Now he channels patient rage into political power, featuring on the air battle-scarred survivors, exhausted caregivers, and the rare insider brave enough to name what's killing us. It’s real stories from real people who refuse to accept that healthcare has to hurt this much. New listeners come for the truth. They stay because finally someone's saying what they've been screaming.
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Out of Patients with Matthew Zachary

Recent Episodes

The Chernobyl Kid in a White Coat: Dr. Yan Leyfman
June 1, 2026

The Chernobyl Kid in a White Coat: Dr. Yan Leyfman

In the late 1980s, a child exposed to fallout from the Chernobyl disaster lay in a hospital bed while doctors told his family there were no clear answers and no reliable path forward. Decades later, that same child, Yan Leyfm...
MZ LIVE at Merkin Concert Hall: 30 Years After Cancer
May 28, 2026

MZ LIVE at Merkin Concert Hall: 30 Years After Cancer

Matthew Zachary is a brain cancer survivor, healthcare advocate, founder of Stupid Cancer and We the Patients, and host of Out of Patients. In April 2026, he returned to the stage at Merkin Hall near Lincoln Center for his fi...
Fatal to Relentless: Kathy Giusti
May 25, 2026

Fatal to Relentless: Kathy Giusti

In December 1996, a 37 year old pharmaceutical executive sat in a Borders bookstore reading medical textbooks on the floor, trying to understand a disease she had never heard of. Multiple myeloma carried a three year prognosi...

About the Host

Matthew Zachary Profile Photo
Matthew Zachary

Producer

Matthew Zachary invented healthcare podcasting before podcasting was a thing. In 2007, fresh off building Stupid Cancer, he grabbed a mic, launched The Stupid Cancer Show and started broadcasting patient stories on internet talk radio when everyone else was still writing blogs.

17 years and 400+ episodes later, Out of Patients is still the most unfiltered healthcare show anywhere.

Matthew doesn't do softball interviews. Brain cancer at 21 taught him that time is finite and bullshit is expensive. He gets guests to say things they'd never tell Congress. CEOs admit what's broken. Patients name what actually hurts. Scientists explain what industry doesn't want you to know. The conversations other shows won't touch because of sponsor concerns or political correctness.

What makes him different: He's been on both sides of the mic. Featured in documentaries, testified before Congress, keynoted hundreds of conferences.

But he's also been the guy puking from radiation, fighting insurance denials, and watching friends die from paperwork.

That dual perspective creates interviews you won't hear anywhere else. He knows which questions make power squirm because he's asked them from hospital beds and boardrooms both.

No pre-approved questions. No PR handlers. No seven-minute segments. Just real conversations with people brave enough to tell the truth about healthcare. After 17 years, Matthew's still the guy Mark Cuban reposts when he wants to understand what patients actually think.

Still the show where whistleblowers go first. Still asking the questions that make everyone uncomfortable.

Because comfortable conversations don't fix broken systems.